The background - recognize the prolongation of the QT time
There are over 200 drugs from numerous groups of active substances that have an undesirable effect on the natural heart rhythm. Such side effects are particularly common with antiarrhythmics (drugs used to treat cardiac rhythm disorders) such as amiodarone, dofetilide, ibutilide, quinidine, procainamide or sotalol. However, numerous antidepressants, antibiotics, cancer drugs, etc. can also have a negative effect on the heart. As a result, potentially life-threatening (ventricular) cardiac arrhythmias of the Torsade de Pointes type can occur in patients. These can be seen in the ECG as an extension of the so-called QT time.
The project - a new form of health care
QT-Life is funded by the innovation fund of the Federal Joint Committee (G-BA) in the area of "New Forms of Care" with 3.3 million euros. The project was set up to improve the drug safety (AMTS) of patients with QT time-prolonging drugs.
The enrollment in this project and the provision for early detection are carried out by the pharmacies. A new form of care that has never existed before. The pharmacies identify potential patients in the pharmacy when redeeming the prescribed medication if this poses a risk of drug-based QT time prolongation.
Partners in the project are DAK-Gesundheit, the Schleswig-Holstein Pharmacists' Association, the North Medical Association and we, Nambaya, as a technology company. The project is led by the Smartstep Data Institute. The Institute for Health Services Research at the University Medical Center Hamburg-Eppendorf (UKE) is responsible for evaluating the knowledge gained.
The current status - 140 pharmacies are involved
To date, more than 50 pharmacies have already been trained and half of them are already active in the project. Over 140 pharmacies have expressed their interest and are now being gradually supplied with all materials and access - the interest and commitment is great. The goal is to have 3,000 completed patient cases by March 2022.
The process - this is how it works
- Any DAK insured person who receives a QT-relevant drug on prescription from a pharmacy integrated into the project can participate in Schleswig-Holstein.
- The pharmacist will inform the insured person accordingly when reading the prescription and offer free participation in the “QT-life” study. After positive feedback, the drug history is taken with the help of the MediCheck software from Pharma4u and the pharmacist records the personal data.
- Then the participant is glued to the mobile EKG device (Faros from Bittium). The 1-channel ECG measures 24 hours in everyday life and at night, it can also be worn without problems when showering and during sports and is only minimally perceived due to its handy size.
- After the 24 hours have elapsed, the participant visits the pharmacy again. Here he returns the device and the pharmacist uploads the measurement to Nambaya-Medical on a secure server.
- The QT time is extracted from the ECG file and quickly evaluated within a few minutes. A traffic light system is used to carry out the initial assessment, which can be communicated to the patient immediately.
- At the same time, the participating cardiologists receive a notification that a measurement is available for detailed evaluation. The ECG is evaluated cardiologically by accessing the secure server. If the findings are abnormal, they are immediately forwarded to medical care, coordinated by the medical control center of Äg Nord.
The role of Nambaya - we make a fast and secure exchange of data possible
With our intelligent and cloud-based platform Nambaya-Medical, we network patients, pharmacists, cardiologists and medical control centers with each other and make a simple and fast screening process possible. The communication of sensitive health data takes place via our GDPR-compliant platform and server.
- Patient overview
- Assign the ECG recorder to the patient
- Upload measurement data
- Quick evaluation of the QT time
- Patient overview
- Assign case
- Detailed evaluation via Navigator software (Bittium)
- Download report
- Diagnosis by electronic signature
Medical control center
- Patient overview
- Coordination, forwarding of all documents to patients
- Project overview
The measuring device - record easily and precisely
We also use the Faros from Bittium for the QT-Life project, which is perfectly suited to its ease of use. The waterproof ECG recorder, certified as a medical product, records ECG, sleep, breathing and movement data precisely with a measuring power of up to 1,000 Hz. Barely larger than a car key and weighing only 18 grams, it accompanies patients in everyday life and at night without disturbing or restricting movement.